[DOWNLOAD] "Genome Editing" by Toni Cathomen, Matthew Hirsch & Matthew Porteus * Book PDF Kindle ePub Free
eBook details
- Title: Genome Editing
- Author : Toni Cathomen, Matthew Hirsch & Matthew Porteus
- Release Date : January 04, 2016
- Genre: Genetics,Books,Professional & Technical,Medical,
- Pages : * pages
- Size : 4258 KB
Description
This
comprehensive volume explores human genetic engineering its pre-clinical and
clinical applications, current developments, and as treatment for hereditary
diseases. It presents and evaluates the most recent advances in the
understanding of mammalian host DNA repair mechanisms, such as double-strand
break induced gene targeting and mutagenesis, the development of zinc-finger
nucleases, genome editing for neuromuscular diseases, phase integrases, triplex
forming oligonucleotides and peptide nucleic acids, aptamer-guided gene
targeting, AAV gene editing via DSB repair, engineered nucleases and
trinucleotide repeat diseases, and creation of HIV-resistant cells. The
expertly authored chapters contextualize current developments within the
history of genome editing while also discussing the current and potential
safety concerns of this rapidly growing field. Genome Editing: The Next Step in Gene Therapy, the latest
volume in the American Society of Gene and Cell Therapy series, deftly illuminates the
potential of genetic engineering technology to eradicate today’s deadliest and
most prolific diseases. It is ideal reading for clinicians and researchers in
genetics and immunology.